Marcello Maggiolini Selected Research

Collagen Receptors

1/2021	DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System.
8/2016	Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells.
2/2016	IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway.

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Marcello Maggiolini Research Topics

Disease

90	Neoplasms (Cancer) 11/2023 - 07/2002
80	Breast Neoplasms (Breast Cancer) 07/2023 - 07/2002
10	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2011
9	Triple Negative Breast Neoplasms 05/2024 - 01/2014
9	Hypoxia (Hypoxemia) 01/2022 - 01/2011
6	Carcinogenesis 02/2021 - 05/2004
6	Prostatic Neoplasms (Prostate Cancer) 12/2017 - 11/2002
4	Obesity 11/2023 - 02/2021
4	Ovarian Neoplasms (Ovarian Cancer) 05/2015 - 02/2007
3	Lung Neoplasms (Lung Cancer) 08/2016 - 03/2009
2	Inflammation (Inflammations) 11/2023 - 02/2021
2	Pathologic Processes 01/2023 - 06/2017
2	Carcinoma (Carcinomatosis) 07/2017 - 12/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 03/2016 - 03/2009
1	Type 2 Diabetes Mellitus (MODY) 01/2022
1	Peripheral Arterial Disease 01/2022
1	Hyperinsulinism (Hyperinsulinemia) 01/2022
1	Hyperglycemia 01/2022

Drug/Important Bio-Agent (IBA)

50	Estrogens (Estrogen)FDA Link 09/2023 - 07/2002
43	Estrogen ReceptorsIBA 09/2023 - 07/2002
29	GTP-Binding Proteins (G-Protein)IBA 09/2023 - 12/2012
23	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2023 - 06/2004
15	Hormones (Hormone)IBA 01/2022 - 07/2002
14	LigandsIBA 11/2023 - 11/2002
14	Estrogen Receptor alphaIBA 01/2020 - 07/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2004
10	Insulin (Novolin)FDA Link 11/2023 - 10/2014
9	Insulin-Like Growth Factor I (IGF-1)IBA 02/2021 - 08/2008
8	AndrogensIBA 12/2017 - 07/2002
7	Aromatase (CYP19)IBA 05/2015 - 07/2002
6	ErbB Receptors (EGF Receptor)IBA 01/2022 - 02/2007
6	Tamoxifen FDA LinkGeneric 07/2014 - 03/2006
5	Peptides (Polypeptides)IBA 01/2023 - 06/2017
5	Androgen Receptors (Androgen Receptor)IBA 01/2022 - 11/2002
5	Insulin ReceptorIBA 01/2022 - 01/2021
5	MicroRNAs (MicroRNA)IBA 03/2019 - 06/2015
5	SteroidsIBA 09/2013 - 11/2002
5	Epidermal Growth Factor (EGF)IBA 08/2010 - 08/2008
4	Growth Factor ReceptorsIBA 02/2019 - 12/2008
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2017 - 01/2013
4	Transcription Factors (Transcription Factor)IBA 07/2017 - 03/2009
4	Estradiol (Delestrogen)FDA LinkGeneric 01/2011 - 07/2002
4	afimoxifene (hydroxytamoxifen)IBA 05/2010 - 03/2006
3	Receptor for Advanced Glycation End ProductsIBA 11/2023 - 02/2021
3	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 07/2023 - 02/2016
3	Focal Adhesion Protein-Tyrosine KinasesIBA 06/2022 - 02/2019
3	ChemokinesIBA 01/2022 - 06/2017
3	CytokinesIBA 11/2021 - 04/2016
3	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2014
3	IntegrinsIBA 02/2021 - 11/2010
3	Collagen ReceptorsIBA 01/2021 - 02/2016
3	EnzymesIBA 12/2017 - 07/2002
3	Fatty Acids (Saturated Fatty Acids)IBA 08/2017 - 11/2011
3	IGF Type 1 Receptor (IGF 1 Receptor)IBA 08/2016 - 09/2009
3	AtrazineIBA 04/2016 - 12/2008
3	Oxygen (Dioxygen)IBA 03/2016 - 03/2011
3	Connective Tissue Growth FactorIBA 01/2013 - 03/2009
3	Messenger RNA (mRNA)IBA 08/2010 - 05/2004
3	GenisteinIBA 10/2006 - 11/2002
2	Insulin-Like PeptidesIBA 11/2023 - 01/2020
2	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 04/2014
2	Conditioned Culture MediaIBA 01/2022 - 10/2015
2	Progesterone Receptors (Progesterone Receptor)IBA 01/2022 - 01/2018
2	Protein Isoforms (Isoforms)IBA 11/2021 - 01/2021
2	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 04/2021 - 01/2019
2	Discoidin Domain Receptor 1IBA 01/2021 - 02/2016
2	Somatomedin Receptors (Somatomedin Receptor)IBA 01/2021 - 01/2017
2	ResveratrolIBA 10/2020 - 07/2009
2	Furylfuramide (AF2)IBA 01/2020 - 01/2019
2	Aromatase InhibitorsIBA 12/2018 - 07/2002
2	LipidsIBA 01/2018 - 11/2011
2	Hypoxia-Inducible Factor 1IBA 12/2017 - 01/2013
2	CopperIBA 12/2017 - 10/2015
2	ZincIBA 12/2017 - 01/2017
2	Trace Elements (Biometals)IBA 12/2017 - 01/2017
2	Doxycycline (Periostat)FDA LinkGeneric 09/2017 - 08/2017
2	Vasoconstrictor AgentsIBA 02/2016 - 03/2009
2	PesticidesIBA 05/2015 - 12/2008
2	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 04/2014 - 09/2009
2	3,4-dihydroxyphenylethanol (hydroxytyrosol)IBA 03/2014 - 06/2010
2	oleuropeinIBA 03/2014 - 06/2010
2	titanoceneIBA 01/2014 - 06/2013
2	Caveolin 1IBA 11/2013 - 07/2012
2	bisphenol AIBA 08/2012 - 12/2003
2	ElementsIBA 09/2010 - 02/2007
2	Estrogen Receptor betaIBA 12/2008 - 06/2004
2	QuercetinIBA 06/2004 - 11/2002
2	Phytoestrogens (Phytoestrogen)IBA 06/2004 - 11/2002
2	Steroid Receptors (Steroid Receptor)IBA 06/2004 - 12/2003
1	EstetrolIBA 05/2024
1	EphrinsIBA 07/2023
1	FilaminsIBA 06/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2022
1	Interleukin-8 (Interleukin 8)IBA 01/2022
1	Advanced Glycation End ProductsIBA 01/2022
1	RNA (Ribonucleic Acid)IBA 11/2021
1	Interleukin-11 (Interleukin 11)IBA 11/2021
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 02/2021

Therapy/Procedure

14	Therapeutics 11/2023 - 06/2013
1	Immunotherapy 01/2022